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Bacterial Phylum Spirochaetes
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移除脊椎动物特有的TBP N终端会破坏胎盘β2m-依赖的与母体免疫系统的相互作用

Nicole K Hobbs1, Alla A Bondareva, Sheila Barnett

  • 1Veterinary Molecular Biology, Marsh Laboratories, Montana State University, Bozeman, MT 59717, USA.

Cell
|August 2, 2002
PubMed
概括

在怀孕期间,TATA结合蛋白 (TBP) N端对胎盘发育和母亲的免疫耐受性至关重要. 在小鼠中破坏这个领域会导致胎儿死亡,突出其至关重要的作用.

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