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Updated: Aug 12, 2026

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在表面定聚烯胺中到刷交叉的组合研究

Tao Wu1, Kirill Efimenko, Jan Genzer

  • 1Department of Chemical Engineering, North Carolina State University, Raleigh 27695-7905, USA.

Journal of the American Chemical Society
|August 9, 2002
PubMed
概括

我们开发了一种新方法,以创建具有受控接种密度的定聚合物. 这种技术可以对聚合物结构进行精确的控制,从而研究它们的行为.

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Antifungal Agents01:15

Antifungal Agents

Amphotericin B is a broad-spectrum antifungal agent that exploits structural differences between fungal and mammalian cell membranes. Its amphipathic structure—featuring a hydrophobic polyene-lactone ring and a hydrophilic region containing mycosamine and carboxylic acid groups—enables selective binding to ergosterol, a sterol predominantly found in fungal plasma membranes. This selective interaction underlies the drug’s antifungal activity, although weak binding to cholesterol contributes to...