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Updated: Jun 28, 2026

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需要用于TGFβ/节点信号传输的ARC/Mediator复合体的一个组成部分

Yoichi Kato1, Raymond Habas, Yu Katsuyama

  • 1Division of Neuroscience, Children's Hospital, Department of Neurology, Harvard Medical School, Boston, Massachusetts 02115, USA.

Nature
|August 9, 2002
PubMed
概括

ARC105对TGFβ/Activin/Nodal/Smad2/3信号通路至关重要,将它们与基因转录联系起来. 这种激活剂招募的辅因子 (ARC) 复杂成分通过调解Smad-依赖基因表达来调节发育和瘤发生.

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