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Updated: Jul 6, 2026

The Logic, Experimental Steps, and Potential of Heterologous Natural Product Biosynthesis Featuring the Complex Antibiotic Erythromycin A Produced Through E. coli
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The Logic, Experimental Steps, and Potential of Heterologous Natural Product Biosynthesis Featuring the Complex Antibiotic Erythromycin A Produced Through E. coli

Published on: January 13, 2013

卡利希胺素基因集群及其代型I enediyne PKS 的基因组

Joachim Ahlert1, Erica Shepard, Natalia Lomovskaya

  • 1Laboratory for Biosynthetic Chemistry, Pharmaceutical Sciences Division, School of Pharmacy, University of Wisconsin-Madison, 777 Highland Avenue, Madison, WI 53705, USA.

Science (New York, N.Y.)
|August 17, 2002
PubMed
概括

研究人员克隆了calicheamicin基因集群,揭示了在染色蛋白和非染色蛋白家族中对enediyne生物合成至关重要的共享多基基因合成酶 (PKS).

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