鉴定和消去异常心室肌的异常心室肌
Michel Haïssaguerre1, Morio Shoda, Pierre Jaïs
1Hôpital Haut-Lévêque, Bordeaux-Pessac, France. jacques.clementy@pu.u-bordeaux2.fr
Circulation
|August 21, 2002
概括
在大多数患者中,导管切除成功地消除了源自普尔金耶系统的危及生命的腹腔动触发因素. 这项研究表明,通过有针对性的射频能量传递,可以消除原发性异常心房动.
科学领域:
- 心脏病学 心脏病学
- 电子生理学 电子生理学
- 医疗器械 医疗器械
背景情况:
- 心室动是心脏突然死亡的主要原因.
- 对于复发性原发性异常性心室动的导管切除以前没有报告.
- 识别和消除触发因素对于管理这种情况至关重要.
研究的目的:
- 调查导管切除的可行性,以消除复发性原发性异常性心室动.
- 为了确定心室的起源触发器.
- 评估废除在预防复发方面的长期疗效.
主要方法:
- 27名从原发性异常心房动中恢复生命的患者接受了电生理学测绘.
- 确定为触发器的过早跳动局部存在于普尔金耶系统或心室肌肉中.
- 使用射频除用于消除已识别的触发部位.
主要成果:
- 心室的触发源于23例患者的远端普金尼系统和4例患者的心室肌肉.
- 在所有情况下,射频除成功地消除了早发性心跳.
- 在平均24个月的随访期间,89%的患者在没有抗心律不良药的情况下仍然没有心室动复发.
结论:
- 初级异常心室动通常是由远端普金尼系统的触发器引起的.
- 焦点导管切除是消除这些触发因素的有效策略.
- 这种方法为患有原发性异常心室动的患者提供了潜在的治疗方法.
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