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转录激活的结构基础:CAP-α CTD-DNA复合体

Brian Benoff1, Huanwang Yang, Catherine L Lawson

  • 1Waksman Institute and Department of Chemistry, Howard Hughes Medical Institute, Rutgers University, Piscataway, NJ 08854, USA.

Science (New York, N.Y.)
|August 31, 2002
PubMed
概括

晶体结构揭示了大肠杆菌的催化剂激活蛋白 (CAP) 如何与RNA聚合酶α子单元碳素终端域 (alphaCTD) 相互作用以激活转录. 这种结构性洞察力支持一种简单的基因激活招募机制.

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