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(+) - 桑帕诺利德和 (+) - 达克提洛利德的总合成利用统一的战略

Amos B Smith1, Igor G Safonov, R Michael Corbett

  • 1Contribution from the Department of Chemistry, Monell Chemical Senses Center, and Laboratory for Research on the Structure of Matter, University of Pennsylvania, Philadelphia, Pennsylvania 19104. smithab@sas.upenn.edu

Journal of the American Chemical Society
|September 13, 2002
PubMed
概括

研究人员首次实现 (+) - 桑帕诺利德和 (+) - 达克提洛利德的总合成,这两种新型宏类药物抑制瘤细胞生长. 这些合成使用了对关键结构特征的立体控制方法,推进了癌症研究.

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