预防中风的新证据:科学综述
Sharon E Straus1, Sumit R Majumdar, Finlay A McAlister
1Division of General Internal Medicine, Department of Medicine, University Health Network, Toronto General Hospital, 200 Elizabeth St, ENG 248, Toronto, Ontario, Canada M5G 2C4. sstraus@mtsinai.on.ca
JAMA
|September 18, 2002
概括
有效的中风预防策略存在,用于初级和二级预防. 证据支持血压和高脂血症的管理,以及对心房动和心肌梗塞患者的特定疗法.
科学领域:
- 神经学 神经学
- 心血管医学 心血管医学
- 公共卫生 公共卫生
背景情况:
- 卒中仍然是导致死亡和残疾的主要原因.
- 目前基于证据的中风预防的应用是不一致的.
研究的目的:
- 系统地审查初级和二级中风预防的最新高质量的证据.
- 巩固发现,以改善临床实践.
主要方法:
- 从1998年至2001年,对主要医疗数据库 (MEDLINE,科克伦图书馆,ACP期刊俱乐部) 进行了全面的文献搜索.
- 扫描参考资料和咨询专家,以确保包含所有相关研究.
- 使用已确定的证据水平对已识别的物品进行严格的质量评估.
主要成果:
- 初级预防:有效的策略包括降低血压,治疗高脂血症,治疗心房的抗血栓治疗,以及心肌梗塞后的抗血小板治疗.
- 二次预防:有效的策略包括高血压和高脂血症的管理,心房的抗血栓治疗,抗血小板治疗,以及严重狭窄的手动动脉内关节切除术.
结论:
- 有大量的证据支持许多初级和二级中风预防策略.
- 预防中风是一个关键的公共卫生问题,需要一致应用经过验证的干预措施.
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