国家临床卓越研究所 (NICE) 决策的合理框架
Karl Claxton1, Mark Sculpher, Michael Drummond
1Department of Economics and Related Studies, University of York, Heslington, York, UK. kpc1@york.ac.uk
Lancet (London, England)
|September 21, 2002
概括
这项研究引入了一个新的框架,以帮助卫生当局决定何时采用基于证据的新健康技术. 它指导决定是否批准技术或要求更多的研究以进行未来的评估.
科学领域:
- 卫生经济学 卫生经济学
- 卫生技术评估 卫生技术评估
- 监管科学是一种监管科学.
背景情况:
- 由于证据的不确定性,监管和报销机构在采用新健康技术方面面临挑战.
- 关于采用技术的决定往往将证据的充分性与进一步研究的必要性混为一谈.
研究的目的:
- 为评估卫生技术提供分析框架.
- 根据当前的证据和对未来研究的需求,区分采用决策.
- 引导监管和报销机构在他们的决策过程中.
主要方法:
- 开发了一个分析框架,将采用决策与研究需求分开.
- 将框架应用于一个涉及新的阿尔茨海默病药物治疗的案例研究.
- 用于案例研究应用程序的已发表的分析.
主要成果:
- 该框架表明,根据技术特征,证据要求有很大差异.
- 需要的证据的数量和类型在卫生技术之间存在很大差异.
- 该框架有助于有效设计未来的研究研究.
结论:
- 拟议的框架为医疗技术评估提供了一个结构化的方法.
- 它为有关技术采用的监管和报销决策提供了清晰度.
- 该框架支持基于证据的决策,并优化研究投资.
相关概念视频
Nursing Interventions II: Selecting and Classifying the Nursing Interventions
Creating and executing a nursing diagnosis helps nurses plan care and guide patient, family, and community interventions. They are developed based on a patient's physical evaluation and support measuring the outcomes. It is not recommended to select random interventions throughout the planning process. Instead, consider the following six essential factors when choosing interventions:
Decision Making: P-value Method
The process of hypothesis testing based on the P-value method includes calculating the P- value using the sample data and interpreting it.
First, a specific claim about the population parameter is proposed. The claim is based on the research question and is stated in a simple form. Further, an opposing statement to the claim is also stated. These statements can act as null and alternative hypotheses: a null hypothesis would be a neutral statement while the alternative hypothesis can have a...
First, a specific claim about the population parameter is proposed. The claim is based on the research question and is stated in a simple form. Further, an opposing statement to the claim is also stated. These statements can act as null and alternative hypotheses: a null hypothesis would be a neutral statement while the alternative hypothesis can have a...
Study Design in Statistics
A study design is a set of techniques that allow a researcher to collect and analyze data from different variables defined for a specific research problem. Statistics is commonly for effective study design and more robust experiments,
Does aspirin reduce the risk of heart attacks? Is one brand of fertilizer more effective at growing roses than another? Is fatigue as dangerous to a driver as the influence of alcohol? Questions like these are answered using randomized experiments with proper...
Does aspirin reduce the risk of heart attacks? Is one brand of fertilizer more effective at growing roses than another? Is fatigue as dangerous to a driver as the influence of alcohol? Questions like these are answered using randomized experiments with proper...
Nursing Clinical Information System
Nursing Clinical Information System (NCIS)
A Nursing Clinical Information System (NCIS) is a specialized type of healthcare information system tailored to meet the unique needs of nursing practice. It incorporates the principles of nursing informatics to streamline information management and improve the quality of care delivery.
Critical attributes of NCIS include:
A Nursing Clinical Information System (NCIS) is a specialized type of healthcare information system tailored to meet the unique needs of nursing practice. It incorporates the principles of nursing informatics to streamline information management and improve the quality of care delivery.
Critical attributes of NCIS include:
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast, controlled...
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast, controlled...
Study Designs in Epidemiology
Epidemiological study designs are fundamental tools for investigating the distribution, determinants, and control of health conditions in populations. They help researchers understand the relationships between exposures and outcomes, and they broadly fall into two categories: "observational" and "experimental" studies.
Observational studies are those where the researcher does not intervene but rather observes natural variations. They include cross-sectional, cohort, and case-control studies.
Observational studies are those where the researcher does not intervene but rather observes natural variations. They include cross-sectional, cohort, and case-control studies.


