苏格兰恶性黑色素瘤的发病率和存活率:一项流行病学研究
Rona M MacKie1, Caroline A Bray, David J Hole
1Departments of Dermatology, University of Glasgow, UK. R.M.Mackie@clinmed.gla.ac.uk
Lancet (London, England)
|September 21, 2002
概括
从1979年至1998年,黑色素瘤发病率在苏格兰显著增加,但由于早期检测了较薄的瘤,生存率有所改善. 建议采取公共卫生干预措施预防黑色素瘤.
科学领域:
- 皮肤病学 皮肤病学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 侵袭性原发性皮肤性恶性黑色素瘤是一个重大的健康问题.
- 评估发病率和生存率对于公共卫生规划至关重要.
研究的目的:
- 评估苏格兰恶性黑色素瘤的发病率和生存趋势.
- 分析黑色素瘤诊断的人口和区域差异.
- 确定早期检测对患者存活率的影响.
主要方法:
- 利用了来自苏格兰黑色素瘤小组的数据,其中包括1979年至1998年期间诊断的8830名患者.
- 分析了年龄标准化的发病率,生存率和死亡率数据.
- 与瘤厚度和检测率相关的生存率改善.
主要成果:
- 年龄标准化的黑色素瘤发病率在男性中增加了303%,在女性中增加了187%.
- 五年生存率显著提高,男性从58%提高到80%,女性从74%提高到85%.
- 生存率的改善主要归因于对较薄的黑色素瘤的诊断.
结论:
- 对于黑色素瘤的初级和二级预防,有必要采取公共卫生干预措施.
- 国家癌症注册表是规划和监测卫生干预措施的宝贵工具.
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