慢性心肌功能障碍的输血和收缩储备:与手术重血管化后的功能性结果的关系
Jeroen J Bax1, Don Poldermans, Arend F L Schinkel
1Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands. jbax@knoware.nl
Circulation
|October 2, 2002
概括
在缺血性心肌病症中评估心肌细胞活力至关重要. 带有收缩储量的完整输液预测了再血管化后的功能恢复,而没有储量的完整输液提供了中间潜力.
科学领域:
- 心脏病学 心脏病学
- 核心脏病学 核心脏病学
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
背景情况:
- 慢性功能障碍的心肌可能保留收缩储备或输液.
- 患有缺血性心肌病的患者往往表现出完整的输液,但在功能障碍的部分缺乏收缩储备.
- 在重血管化后,这些细分的功能结果仍然不清楚.
研究的目的:
- 评估缺血性心肌病患者的收缩储备和输液.
- 为了将这些发现与重血管化后的功能恢复相关联.
主要方法:
- 114名患有缺血性心肌病的患者通过低剂量多布他胺心声学评估了使用静止 (99m) Tc四福斯和收缩储量的输液.
- 收缩功能在手术重血管化前和9-12个月后通过二维回声心脏图进行评估.
主要成果:
- 在1336个功能障碍的细分部分中,51%的细分部分保持了 perfusion,31%的细分部分保持了 contractile reserve.
- 47%的输液段缺乏收缩储备. 47%的输液段缺乏收缩储备.
- 重血管后功能恢复的部分主要具有完整的输液和收缩储备 (66%).
- 没有功能恢复的部分大多缺乏输液和收缩储备 (58%).
- 在有功能恢复的22%的段落和没有功能恢复的25%的段落中观察到没有收缩储备的完整输液.
结论:
- 具有完整的输液和收缩储备的细分部分在重血管化后具有很高的功能恢复概率.
- 缺少透和收缩储备的片段的恢复概率很低.
- 具有完整 perfusion 但没有收缩储备的段落显示功能恢复的中间可能性.
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