在急性缺血性甲状腺吐期间,对后部甲状腺叶片间贝贝间恶性吸收的机制性见解

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David T Lai¹, Frederick A Tibayan, Truls Myrmel

¹Department of Cardiovascular and Thoracic Surgery and Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, Calif., USA.

|October 2, 2002

概括

由于环状扩张,急性缺血性 mitra 反会导致贝的不良吸收. 这项研究测量了三维贝动态,揭示了叶片恶性吸收的机制,并支持了手术修复策略.

科学领域:

心血管研究研究心血管研究
心脏外科手术心脏外科手术
生物医学工程生物医学工程

背景情况:

在急性缺血性 mitrale regurgitation (AIMR) 中,后部 mitrale 叶片的三维 (3D) 动态仍然未得到量化.
了解贝的运动对于解决关节反至关重要.

研究的目的:

在AIMR过程中,测量后部关叶片内单个的3D动态.
为了阐明在AIMR中贝不良吸收的几何机制.

主要方法:

在13只羊中,放射性遮标记物被放置在额头环,乳头肌肉尖端和传单边缘.
高速双平面视频光镜在诱导AIMR之前和期间捕获了3D标记坐标.
急性缺血腹吐是通过阻塞左环冠状动脉而产生的.

主要成果:

在AIMR过程中,观察到中央的前侧边缘侧向 (0.8+/-0.9毫米) 和角向 (0.9+/-0.6毫米) 的末缩位移.
这种移位与侧环形移位和远离乳头尖端的移动相关.
前中侧边缘移位 (1.4+/-0.9毫米前方,0.9+/-0.6毫米侧面) 与中侧环状移位相对应.

结论:

在急性左心室缺血期间,在后侧叶片内发生贝贝的恶性吸收是一种新发现.
环状扩张被确定为主要的几何机制,通过分离叶片引起鱼的恶性吸收.
调查结果支持环状减小和亚委会关闭用于缺血性米特拉吐修复.

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