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在裸金属支架植入后,晚期错位的背景发生率
Vivek M Shah1, Gary S Mintz, Sue Apple
1Intravascular Ultrasound Imaging and Cardiac Catheterization Laboratories, Cardiovascular Research Institute, Washington Hospital Center, Washington, DC 20010, USA.
Circulation
|October 3, 2002
概括
晚期支架错位,支架支架与动脉壁的分离,发生在4%-5%的裸金属支架植入物中. 这一发现通常在支架边缘观察到,并与积极的动脉重塑有关.
科学领域:
- 心血管干预包括心血管干预.
- 医疗器械成像 医疗器械成像
- 生物医学工程 生物医学工程
背景情况:
- 晚期支架错位 (LSM) 是血管支架治疗和药物释放支架植入后的异常发现.
- 在随访期间,需要进行血管内超声波 (IVUS) 检测LSM.
- 裸金属支架 (BMS) 植入后LSM的发生频率尚未确立.
研究的目的:
- 为了确定裸金属支架植入后晚期支架错位 (LSM) 的发生率.
- 调查LSM的特征和位置.
- 在接受BMS的患者中识别LSM的潜在原因.
主要方法:
- 一项对206名患有本地动脉病变的患者进行的研究,这些患者接受了管状槽BMS植入.
- 血管内超声波 (IVUS) 成像在植入时进行,并在6+/-3个月后进行随访.
- LSM的定义: ≥1个支架支架与动脉壁内密 (不包括侧枝) 的分离,植入后的IVUS显示完全的位置.
主要成果:
- 在9名患者 (4.4%) 中发现了晚期支架缺陷 (LSM).
- 主要发生在支架边缘的LSM (9名患者中有8名).
- 观察到外部弹性膜 (EEM) 和斑块面积增加,EEM扩张超过斑块生长,与LSM面积相关.
结论:
- 晚期支架错位 (LSM) 发生在4 - 5%的槽管裸金属支架中,经常发生在支架边缘.
- LSM的主要驱动因素是积极的动脉重塑,这与周围静脉内膜增多不成比例.
- 在BMS植入后,IVUS对于识别LSM至关重要.
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