人类动态大脑自我调节的自主神经控制
Rong Zhang1, Julie H Zuckerman, Kenichi Iwasaki
1Institute for Exercise and Environmental Medicine, Presbyterian Hospital of Dallas, and the University of Texas Southwestern Medical Center at Dallas, Tex 75231, USA.
Circulation
|October 3, 2002
概括
自主神经控制显著影响动态大脑自我调节. 节阻塞改变了大脑血流调节,这表明性自主活动对于节拍控制至关重要.
科学领域:
- 身体生理学 身体生理学
- 神经科学是一个神经科学.
- 心血管研究研究心血管研究
背景情况:
- 自主神经控制对于维持稳定的生理功能至关重要.
- 动态大脑自调节在血压波动期间保护大脑功能.
研究的目的:
- 研究自主神经控制在动态大脑自我调节中的作用.
- 评估自主阻塞如何影响大脑血流调节.
主要方法:
- 12名健康受试者接受了用三甲基进行的节阻塞.
- 测量了动脉压和中脑动脉血流速度.
- 转移函数分析量化了动态大脑自我调节.
主要成果:
- 节阻塞降低了血压和大脑血流速度.
- 自主封锁增加了转移功能的增益和相位的减少,表明大脑自调节的动态受损.
- 即使在血压正常化后,这些变化仍然存在.
结论:
- 动态大脑自我调节被自主阻塞显著改变.
- 大脑循环的自主神经控制是有力活跃的.
- 自主控制在节拍调节大脑血流方面发挥着关键作用.
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