SET:

Todd O Yeates1

  • 1UCLA Molecular Biology Institute and Department of Chemistry and Biochemistry, UCLA-DOE Center for Genomics and Proteomics, 611 Charles Young Dr. East, Box 951570, Los Angeles, CA 90095, USA. yeates@mbi.ucla.edu

Cell
|October 10, 2002
PubMed
概括

SET 域蛋白质甲基化 lysine 残留物. 新的3D结构揭示了新的折叠和对这些酶的催化和分子识别的洞察.

相关概念视频

Conservation of Protein Domains Over Different Proteins02:26

Conservation of Protein Domains Over Different Proteins

Protein domains are small structurally independent units that are part of a single amino acid chain.  Although these domains are often structurally independent, they may rely on synergistic effects to perform their functions as part of a larger protein. Protein domains may be conserved within the same organism, as well as across different organisms.
A limited set of protein domains often duplicate and recombine during evolution. These domains can be organized in different combinations to...
14.6K
Protein and Protein Structure02:15

Protein and Protein Structure

Proteins are one of the most abundant organic molecules in living systems and have the most diverse range of functions of all macromolecules. Proteins may be structural, regulatory, contractile, or protective. They may serve in transport, storage, or membranes; or they may be toxins or enzymes. Their structures, like their functions, vary greatly. They are all, however, amino acid polymers arranged in a linear sequence.
A protein's shape is critical to its function. For example, an enzyme...
88.2K
Structural Protein Function01:56

Structural Protein Function

Structural proteins are a category of proteins responsible for functions ranging from cell shape and movement to providing support to major structures such as bones, cartilage, hair, and muscles. This group includes proteins such as collagen, actin, myosin, and keratin.
Collagen, the most abundant protein in mammals, is found throughout the body. In connective tissue, such as skin, ligaments, and tendons, it provides tensile strength and elasticity.  In bones and teeth, it mineralizes to...
30.0K
Structural Protein Function01:56

Structural Protein Function

No description available
3.3K
Conservation of Protein Domains02:26

Conservation of Protein Domains

No description available
4.1K
Protein and Protein Structures02:15

Protein and Protein Structures

No description available
19.2K