骨密度计的临床应用:临床应用
David W Bates1, Dennis M Black, Steven R Cummings
1Department of Medicine, Brigham and Women's Hospital, and the Center for Applied Medical Information Systems Research, Partners Healthcare Systems, and Harvard Medical School, Boston, Mass 02115, USA. dbates@partners.org
JAMA
|October 17, 2002
概括
对医生来说,解读骨质疏松症测试结果仍然具有挑战性,导致诊断不足和治疗不足. 更清晰的报告和风险因素评估工具可以改善骨质疏松症查和患者管理.
科学领域:
- 骨健康和代谢障碍 骨健康和代谢障碍
- 临床诊断和查 临床诊断和查
背景情况:
- 骨质疏松症的诊断因难以解释测试结果而复杂化.
- 许多患有骨质疏松症查明显迹象的患者没有被识别或治疗.
研究的目的:
- 解决骨质疏松症查和诊断方面的挑战.
- 改善骨质疏松症诊断测试的解释和应用.
主要方法:
- 对目前基于证据的骨质疏松症查指南的审查.
- 对影响测试结果解释和患者鉴定因素的分析.
- 考虑提高查效率的策略,例如风险因素问卷和基于护士的系统.
主要成果:
- 指导方针建议针对特定的人口统计数据进行查,但遵守是不一致的.
- 由于诊断的复杂性,患者的鉴定和治疗是不理想的.
- 更清晰的测试结果报告可以增加测试并减少混.
结论:
- 医生需要改进的方法来识别患者谁将受益于骨质疏松症查.
- 需要系统来促进查的应用和简化测试结果的解释.
- 强化策略对于有效的骨质疏松症管理至关重要.
相关概念视频
Bone Remodeling
Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
X-ray Imaging
German physicist Wilhelm Röntgen (1845–1923) was experimenting with electrical current when he discovered that a mysterious and invisible "ray" would pass through his flesh but leave an outline of his bones on a screen coated with a metal compound. In 1895, Röntgen made the first durable record of the internal parts of a living human: an "X-ray" image (as it came to be called) of his wife’s hand. Scientists worldwide quickly began their own experiments with X-rays, and by 1900, X-ray was widely...
Bone Disorders
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Hormones and Bone Tissue
The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT
Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...


