严重心力衰竭的顺序与同时双心室重同步:通过组织多普勒成像评估
Peter Sogaard1, Henrik Egeblad, Anders K Pedersen
1Department of Cardiology, Aarhus University Hospital, Skejby Sygehus, Aarhus, Denmark. psogaard@dadlnet.dk
Circulation
|October 16, 2002
概括
顺序心脏再同步疗法 (CRT) 通过优化双心室节奏延迟,显著提高心脏功能. 这种方法改善了心力衰竭患者的缩和腹缩性能.
科学领域:
- 心脏病学 心脏病学
- 生物医学工程 生物医学工程
背景情况:
- 使用双心室节奏的心脏再同步疗法 (CRT) 改善了心力衰竭的结果.
- 同时节奏是标准的,但最佳时机仍在争论中.
研究的目的:
- 用组织追踪和3D心声回声学来评估连续的CRT.
- 为了确定个性化静脉间延迟编程对心脏表现的影响.
主要方法:
- 20名心力衰竭和捆绑分支阻塞的患者接受了CRT.
- 组织跟踪和3D回声心脏学评估了节拍前后心肌收缩.
- 测试了多个腹腔间延迟,以找到最佳的顺序编程.
主要成果:
- 顺序CRT显著减少延迟纵向收缩 (DLC) 和增加左心室喷射率 (LVEF%).
- 与同步CRT相比,最佳顺序CRT进一步改善了DLC和LVEF%.
- 三个月的随访显示,随着连续的CRT,LVEF%的持续改善.
- 连续的CRT增加了7%的透析填充时间.
结论:
- 顺序CRT在抽缩和放缩性能方面比同步CRT提供了显著的优势.
- 组织跟踪对于优化CRT中腹腔间延迟是有效的.
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