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Updated: Jul 21, 2026

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尼古丁乙胆受体的结合部位的扰乱的pK:对尼古丁结合的含义

E James Petersson1, Anita Choi, David S Dahan

  • 1Division of Chemistry and Chemical Engineering, Division of Biology, California Institute of Technology, Pasadena 91125, USA.

Journal of the American Chemical Society
|October 24, 2002
PubMed
概括

研究人员使用绑定的激动剂制造了自开门的尼古丁乙胆受体 (nAChRs). 这些修改后的受体表现出pH值依赖的活动,pH值较低可逆地激活受体,影响药理学研究.

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