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Development of a Backbone Cyclic Peptide Library as Potential Antiparasitic Therapeutics Using Microwave Irradiation
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14螺旋抗微生物β-的结构-活性研究:探讨构造稳定性和抗微生物功效之间的关系

Tami L Raguse1, Emilie A Porter, Bernard Weisblum

  • 1Department of Chemistry and Department of Pharmacology, University of Wisconsin, Madison 53706, USA.

Journal of the American Chemical Society
|October 24, 2002
PubMed
概括

具有不同螺旋稳定的β-具有与细菌相比较的抗微生物活性. 虽然螺旋倾向影响溶血活性,但这些β为研究宿主防御中的结构-活性关系提供了一个独特的平台.

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