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Y染色体AZFc缺失的传播的影响

Philippos C Patsalis1, Carolina Sismani, Lluis Quintana-Murci

  • 1Cyprus Institute of Neurology and Genetics, Cyprus.

Lancet (London, England)
|October 29, 2002
PubMed
概括

经常与男性不孕症相关的Y染色体微删除在三分之一的特纳印或性模两可的患者中被发现. 这表明,继承这些缺陷的后代可能会面临不孕症以外的严重临床后果.

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Epistasis01:39

Epistasis

In addition to multiple alleles at the same locus influencing traits, numerous genes or alleles at different locations may interact and influence phenotypes in a phenomenon called epistasis. For example, rabbit fur can be black or brown depending on whether the animal is homozygous dominant or heterozygous at a TYRP1 locus. However, if the rabbit is also homozygous recessive at a locus on the tyrosinase gene (TYR), it will have an unshaded coat that appears white, regardless of its TYRP1...