基替代基和基在Ru(2) S(2) 复合体上的脱水反应
Kazuko Matsumoto1, Yoshihiro Moriya, Hiroyasu Sugiyama
1Department of Chemistry, School of Science and Engineering, and Advanced Research Institute of Science and Engineering, Waseda University and Japan Science and Technology Corporation, 3-4-1 Ohkubo, Shinjuku, Tokyo 169-8555, Japan. kmatsu@waseda.jp
Journal of the American Chemical Society
|October 31, 2002
概括
复合物与基替代的基和基反应,经过脱水形成新的C-S环结构. 这项研究探讨了分子间和分子内反应,产生各种有机金属复合体.
科学领域:
- 有机金属化学 有机金属化学
- 协调化学 协调化学
- 合成化学 合成化学
背景情况:
- 复合物是有机合成中的多功能催化剂.
- 脱水反应对于形成新的化学键和循环结构至关重要.
- 了解含硫复合物的反应性对于开发新的合成方法至关重要.
研究的目的:
- 为了研究一种特定的鲁复合物的反应,[ Ru .
- 阐明这些反应中分子间和分子内脱水的机制.
- 合成和描述含有的新型循环复合物.
主要方法:
- 复合物1与醇,3--1-醇,2--1-醇,2--1-醇和各种二醇的反应.
- 使用光谱技术分离和描述中间和最终产品.
- 对反应途径的分析,包括C-H键激活和脱水.
主要成果:
- 通过分子间脱水和用醇激活C-H,形成一个C(3) S(2) 五个环复合体 (2).
- 一个C(4) S(2) 六个环复合物的合成 (3) 通过与3--1-ol的分子内脱水.
- 从与醇的反应中生成同质合和交叉合产物 (4-7),涉及分子间脱水.
- 从与二醇和甲基替代基的反应中形成基复合物 (8-9) 和其他独特结构 (10-11),表现出多种脱水和S-S键裂解途径.
结论:
- 鲁复合物1有效调解与不和酒精的分子间和分子内脱水反应.
- 这项研究证明了多种循环有机金属结构的形成,突出了这种复合物的合成化学中的实用性.
- 观察到的反应提供了对C-S键形成,C-H激活和涉及的新型循环化策略的见解.
相关概念视频
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