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Updated: Jul 17, 2026

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通过和转移差的NMR实验在D(2) O和H(2) O中检测连接物与小RNA标的结合

Moriz Mayer1, Thomas L James

  • 1Department of Pharmaceutical Chemistry, University of California, San Francisco 94143-0446, USA.

Journal of the American Chemical Society
|November 7, 2002
PubMed
概括

和转移差异 (STD) NMR有效地使用小RNA动机选RNA-配体相互作用. 氧化 (D2O) 溶剂通过降低放松率来增强检测,提高药物发现的查效率.

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