选择的主要风险因素以及疾病的全球和区域负担
Majid Ezzati1, Alan D Lopez, Anthony Rodgers
1Risk, Resources and Environmental Management Division, Resources for the Future, Washington, DC, USA.
Lancet (London, England)
|November 9, 2002
概括
体重不足,不安全的性行为和高血压等重大健康风险对全球疾病负担作出了重大贡献,特别是在发展中国家. 解决这些因素为公众健康带来了巨大的好处.
科学领域:
- 全球健康 全球健康
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 准确的健康风险分析对于预防疾病至关重要.
- 传统的风险因子归因限制了可比性.
- 全球和区域疾病负担分析需要一个统一的框架.
研究的目的:
- 估计主要风险因素对全球和区域疾病负担的贡献.
- 建立一个统一的风险因素分析框架.
- 通过量化风险因素影响,为公共卫生战略提供信息.
主要方法:
- 审查了14个流行病学地区26个风险因素的已公布数据和数据库.
- 估计人口归因分数使用潜在影响分数关系.
- 将发现应用于全球疾病负担 (GBD) 估计的死亡率和疾病负担.
主要成果:
- 儿童/母亲体重不足,不安全的性行为,高血压,烟草和酒精是全球疾病负担的主要原因.
- 最贫穷的地区不成比例地受到体重不足,不安全的性行为,卫生条件差,室内烟雾和缺陷的影响.
- 酒精,烟草,高血压和高胆固醇是发展中国家和发达地区的主要负担.
结论:
- 主要风险对全球疾病负担做出了重大贡献,超过了之前的估计.
- 发展中国家承担了许多主要风险因素的重担.
- 针对这些已识别的风险可以产生显著的,低估的公共卫生收益.
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