饮用水急剧改善了健康人群的静止性耐受性
Christoph Schroeder1, Victoria E Bush, Lucy J Norcliffe
1Franz-Volhard Clinical Research Center, Medical Faculty of the Charité, Humboldt-University, Berlin, Germany.
Circulation
|November 27, 2002
概括
饮用500毫升水通过增强血液动力学反应和大脑血流调节,显著改善健康个体的静态耐受性. 这种简单的干预可以帮助预防起立时头和昏等症状.
科学领域:
- 生理学 生理学 生理学
- 心血管科学 心血管科学
- 自主神经系统功能 自主神经系统功能
背景情况:
- 静态症状和昏迷很普遍,影响健康人群和自主功能障碍的人群.
- 已知摄入水可诱导压力反应,并减轻严重自主功能障碍患者的正静性低血压.
研究的目的:
- 为了研究饮用水对健康受试者的静止性耐受性的影响.
- 为了确定急性饮水是否可以提高身体维持血压的能力,并防止站立时昏倒.
主要方法:
- 一项随机,受控,交叉研究,涉及13名健康受试者.
- 试验对象在经历头部向上倾斜和身体下部负压之前,先摄入500毫升或50毫升矿泉水.
- 测量包括手指和手臂血压,心率,胸部阻抗和脑血流速度.
主要成果:
- 摄入500毫升的水显著增加了正静性耐受度,平均为5分钟 (P<0.001).
- 这种摄入的水量导致卧式血压略微增加,原因是周围阻力升高.
- 在静止性压力期间,饮用水减轻了心率增加和中风体积减少,改善了大脑血流调节.
结论:
- 饮用水触发了即时的血液动力学反应,并改变了健康个体的大脑血管调节.
- 这些生理变化直接与耐受直立姿势的能力大幅改善有关.
关键词:
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