在人类中,向心节点输入左心室输入的演示
Mario D Gonzalez1, Leonardo J Contreras, Francisco Cardona
1Division of Cardiovascular Medicine, University of Florida College of Medicine, Gainesville, FL 32610-0277, USA. gonzamd@medicine.ufl.edu
Circulation
|December 4, 2002
概括
mitra annulus 是一个关键的途径,用于左心房激活心房 (AV) 节点在人类. 这项研究澄清了向AV节点的左心房输入,进步了对心脏电生理学的理解.
科学领域:
- 心脏病学 心脏病学
- 心脏电生理学 心脏电生理学
- 人体生理学 人体生理学
背景情况:
- 内心心室 (AV) 节点接收前置和后置右心房刺激的输入.
- 了解到AV节点的左心房激活通路对于理解心脏导电至关重要.
研究的目的:
- 为了研究从左心房到人体中AV节点的电激活路径.
主要方法:
- 在46名心脏正常的患者中研究了AV结节导电,使用右心房和左心房 (冠状动脉鼻) 刺激.
- 在各种节拍协议期间测量了A-H间隔并分析了在His捆附近的心房电图.
- 在不同位置利用晚期心房外刺激来评估激活时间.
主要成果:
- 与右心房刺激相比,左心房刺激导致A-H间隔显著缩短 (73毫秒对99毫秒).
- 在inferoparaseptal mitra annulus的刺激推进了心房和他的捆绑激活,表明左侧输入.
- 来自前后两种方法的外刺激并没有改变His捆绑激活时间,与 mitra annulus刺激不同.
结论:
- mitra annulus 作为一个关键的左心房输入部位,进入人体AV节点.
- 这一发现揭示了以前人们对心脏电导的理解较少的途径.
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