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Updated: Jul 18, 2026

Unraveling Entropic Rate Acceleration Induced by Solvent Dynamics in Membrane Enzymes
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溶性环氧化酶的反应机制:从分子动力学模拟的见解

Birgit Schiøtt1, Thomas C Bruice

  • 1Department of Chemistry, Aarhus University, 8000 Aarhus, Denmark. birgit@chem.au.dk

Journal of the American Chemical Society
|December 6, 2002
PubMed
概括

分子动力学模拟揭示了可溶性环氧化酶 (sEH) 如何催化反应. 一种质子化胺对于活性位点的稳定性至关重要,而Tyr465通过键引导基质的区域选择性.

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Heterogeneous Catalysis

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