相关实验视频

Updated: Jun 7, 2026

Iterative Optimization of DNA Duplexes for Crystallization of SeqA-DNA Complexes
11:42

Iterative Optimization of DNA Duplexes for Crystallization of SeqA-DNA Complexes

Published on: November 1, 2012

辅助核酸晶体学:使用酸酸酸盐用于DNA结构的MAD分相

Christopher J Wilds1, Rekha Pattanayek, Chongle Pan

  • 1Department of Biological Sciences, Vanderbilt University, Nashville, TN 37235, USA.

Journal of the American Chemical Society
|December 12, 2002
PubMed
概括

素酸盐简化了在X射线晶体学中将异常散射物引入DNA. 这种方法避免了复杂的合成,使得核酸的结构能够有效地确定.

更多相关视频

Probing The Structure And Dynamics Of Nucleosomes Using Atomic Force Microscopy Imaging09:52

Probing The Structure And Dynamics Of Nucleosomes Using Atomic Force Microscopy Imaging

Published on: January 31, 2019

Probing RNA Structure with Dimethyl Sulfate Mutational Profiling with Sequencing In Vitro and in Cells10:34

Probing RNA Structure with Dimethyl Sulfate Mutational Profiling with Sequencing In Vitro and in Cells

Published on: December 9, 2022

相关概念视频

Maxam-Gilbert Sequencing01:05

Maxam-Gilbert Sequencing

In the same year as the discovery of the Sanger sequencing method, another group of scientists, Allan Maxam and Walter Gilbert, demonstrated their chemical-cleavage method for DNA sequencing. The Maxam-Gilbert method relies on using different chemicals that can cleave the DNA sequence at specific sites, the separation of resulting DNA fragments of variable size using electrophoresis, and deciphering the DNA sequence from the resulting gel bands.
Challenges of the Maxam-Gilbert Method
The...