鱼类消费与男性中风风险
Ka He1, Eric B Rimm, Anwar Merchant
1Department of Nutrition, Harvard School of Public Health, 665 Huntington Ave, Boston, Mass 02115, USA. khe@hsph.harvard.edu
JAMA
|December 27, 2002
概括
每月至少吃一次鱼可以显著降低男性缺血性中风的风险. 较高的鱼类消费并没有为预防中风提供额外的益处.
科学领域:
- 心血管流行病学心血管流行病学
- 营养科学 营养科学
- 公共卫生 公共卫生
背景情况:
- 鱼类消费,omega-3脂肪酸和中风风险之间的关联尚未得到充分证实.
- 关于饮食中长链多不和脂肪酸 (PUFA) 对脑血管疾病的影响存在不确定性.
研究的目的:
- 为了研究鱼类摄入量,长链欧米茄-3 PUFA 摄入量和男性中风发病率之间的关系.
- 澄清饮食因素在中风风险分层中的作用.
主要方法:
- 前性队列研究 (健康专业人员随访研究) 涉及43671名男性,持续了12年.
- 利用经过验证的食物频率调查问卷来评估饮食摄入量,包括鱼和omega-3PUFAs.
- 分析了基于累计饮食摄入量的中风亚型的相对风险 (RR).
主要成果:
- 每月至少食用一次鱼类的男性患缺血性中风的风险显著降低 (RR,0.56).
- 每月超过一次增加鱼类摄入量并没有进一步降低缺血性中风的风险.
- 没有观察到鱼类摄入量与出血性中风风险之间的显著关联.
结论:
- 每月或更频繁地食用鱼与男性缺血性中风风险降低有关.
- 饮食中的鱼类摄入量代表了对缺血性中风的初级预防的可修改因素.
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