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Updated: May 3, 2026

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人体素甲基转移酶SET7/9的结构和催化机制

Bing Xiao1, Chun Jing, Jonathan R Wilson

  • 1Structural Biology Group, National Institute for Medical Research, Mill Hill, London NW7 1AA, UK.

Nature
|January 24, 2003
PubMed
概括

人类SET7/9是一种独特的单甲基酶,与其他SET蛋白不同. 它的晶体结构揭示了素标和辅因子的结合方式,解释了甲基化特异性和反应机制.

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