甲状腺癌是一种甲状腺癌
1Department of Endocrine Neoplasia and Hormonal Disorders, University of Texas MD Anderson Cancer Center, Texas, Houston 77030, USA. sisherma@mdanderson.org
Lancet (London, England)
|February 14, 2003
概括
甲状腺癌的治疗包括手术和放射性,甲状腺激素抑制有助于预防复发. 对于晚期甲状腺癌,需要新型疗法,基因测试有助于遗传综合征.
科学领域:
- 在瘤学瘤学.
- 内分泌学 在内分泌学.
背景情况:
- 甲状腺癌是罕见的,从无动于衷的乳头癌到致命的厌塑性类型.
- 对于诊断和初步管理,已有确立的指南,经常建议使用多模式治疗.
- 来自前性试验的证据支持多模式方法是有限的.
研究的目的:
- 总结目前对甲状腺癌的理解和治疗.
- 突出需要改善治疗先进和高风险甲状腺癌的必要性.
- 强调基因检测在遗传性甲状腺癌综合征中的作用.
主要方法:
- 对甲状腺癌当前治疗策略的审查.
- 讨论手术切除,放射性治疗和甲状腺激素抑制.
- 考虑遗传甲状腺癌综合征的基因检测.
主要成果:
- 手术切除是局部控制的主要治疗方法.
- 辅助放射性治疗对于乳头和卵泡类型是常见的.
- 抑制甲状腺激素可以防止特定类型甲状腺癌的复发.
- 对于渐进的转移性疾病存在有限的益处,需要新的治疗策略.
结论:
- 多学科的护理和患者教育对于明智的决策至关重要.
- 早期诊断和干预,特别是在遗传性综合征中,可以改善结果.
- 对侵袭性和转移性甲状腺癌的新型治疗方法有显著的需求.
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