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Updated: Jul 6, 2026

Detection of In Situ Protein-protein Complexes at the Drosophila Larval Neuromuscular Junction Using Proximity Ligation Assay
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蛋白质组屏幕发现了pSer/pThr结合域,将Plk1定位到线粒基质上

Andrew E H Elia1, Lewis C Cantley, Michael B Yaffe

  • 1Center for Cancer Research, Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

Science (New York, N.Y.)
|February 22, 2003
PubMed
概括

研究人员确定了一种特定的结合基因,用于波罗样酶1 (Plk1) 的波罗盒域 (PBD). 这一发现解释了Plk1激酶如何通过Cdk酸化定位到细胞部位,准其基质.

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