慢性淋巴细胞白血病和霍奇金病的同时存在. 一个案例报告报告
1Department of Pathology, University Hospital, New York University Medical Center, New York, USA.
JAMA
|March 7, 1966
概括
本病例报告详细介绍了一种罕见的慢性淋巴细胞白血病和霍奇金病共存的罕见病例,呈现出异常高的白细胞计数. 该患者对慢性淋巴细胞白血病的标准治疗反应有限.
科学领域:
- 血液学 血液学 血液学
- 在瘤学瘤学.
- 病理学 病理学 病理学
背景情况:
- 不同的淋巴增殖性疾病的同时存在并不常见.
- 了解不同淋巴细胞恶性瘤之间的关系是一个正在进行的研究领域.
- 高白细胞计数可能表明有侵略性的血液学状况.
研究的目的:
- 报告一个独特的同时患有慢性淋巴细胞白血病和霍奇金病的病例.
- 突出这种共存所带来的诊断和治疗挑战.
- 为促进关于淋巴增殖性疾病关系的讨论做出贡献.
主要方法:
- 案例研究分析.
- 审查患者的临床病史和治疗反应.
- 尸体解剖结果证实了这两种诊断.
主要成果:
- 确认了慢性淋巴细胞白血病和霍奇金病在同一患者的同时存在.
- 观察到与霍奇金病相关的异常高的白细胞数量 (213,000/cu mm).
- 记录了对各种化疗剂和慢性淋巴细胞白血病的普得尼松的不利和短暂的反应.
结论:
- 慢性淋巴细胞白血病和霍奇金病的同时发生是罕见的,并带来诊断挑战.
- 在这种情况下,高白细胞计数是值得注意的,需要进一步调查其影响.
- 这一案例凸显了淋巴增殖性疾病的复杂性和对它们的相互关系的持续研究的需要.
相关概念视频
Disorders of Leukocytes
Leukocyte disorders can lead to either leukopenia, characterized by an abnormally low leukocyte count, or leukocytosis, marked by a very high leukocyte number.
Leukopenia may result from bone marrow disorders, autoimmune diseases, and infectious diseases. For example, conditions such as multiple myeloma and aplastic anemia can impair the bone marrow's ability to produce adequate leukocytes. Similarly, autoimmune diseases like lupus and viral infections such as HIV can prompt the immune system...
Leukopenia may result from bone marrow disorders, autoimmune diseases, and infectious diseases. For example, conditions such as multiple myeloma and aplastic anemia can impair the bone marrow's ability to produce adequate leukocytes. Similarly, autoimmune diseases like lupus and viral infections such as HIV can prompt the immune system...
Bone Marrow Sampling and Transplants
Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...
Immunodeficiency Diseases
Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency disorders...
There are three main causes of immunodeficiency disorders...
Pulmonary Tuberculosis I
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...


