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Updated: Jul 11, 2026

Multi-parameter Measurement of the Permeability Transition Pore Opening in Isolated Mouse Heart Mitochondria
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Published on: September 7, 2012

MCC-134是一种单一的药,打开了 ATP 敏感的表面通道,阻断了线粒体 ATP 敏感的通道,并抑制了预先调节

Norihito Sasaki1, Mitsushige Murata, Yiru Guo

  • 1Laboratory of the Institute of Molecular Cardiobiology, Johns Hopkins University, Baltimore, MD 21205, USA.

Circulation
|March 5, 2003
PubMed
概括

MCC-134打开心脏表面通道,但抑制线粒体通道. 这种药物阻断了预调的心脏保护作用,突出了线粒体K ((ATP) 通道在心脏保护中的作用.

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