Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关实验视频

工程进化是为了研究酵母菌中的物种化.

Daniela Delneri1, Isabelle Colson, Sofia Grammenoudi

  • 1School of Biological Sciences, University of Manchester, 2.205 Stopford Building, Oxford Road, Manchester M13 9PT, UK.

Nature
|March 7, 2003
PubMed
概括
此摘要是机器生成的。

在Saccharomyces酵母中发生的基因组重组会影响杂交活力. 在Saccharomyces cerevisiae和Saccharomyces mikatae基因组之间强加的直线性导致了可行的但无体杂交,这表明在物种化中的作用.

相关实验视频

相关概念视频

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Yeast at Forty.

Yeast (Chichester, England)·2026
Same author

EASY-C: Extraction and Analysis of Small Yeast Chromosomes-A rapid and universal platform for recovering artificial mini-chromosomes from synthetic Sc2.0 yeast and large plasmids from <i>Saccharomyces cerevisiae</i> and nonconventional yeast species.

Synthetic biology (Oxford, England)·2026
Same author

Genome-wide discovery and phenotyping of non-coding transcripts in A. fumigatus reveals lncRNAs with a role in antifungal drug sensitivity.

Nature communications·2026
Same author

Construction of a reference genome for Starmerella batistae and annotation of Starmerella species reveal an unexpected evolutionary relationship with Schizosaccharomyces pombe and suggest an alternative enzymatic route for sophorolipid production.

FEMS yeast research·2026
Same author

Versican expression from lung fibroblasts suppresses pulmonary fibrosis.

Nature communications·2026
Same author

Advances and challenges in understanding evolution through genome comparison: meeting report of the European Molecular Biology Organization (EMBO) lecture course "Evolutionary and Comparative Genomics".

Bioinformatics advances·2025
Same journal

Daily briefing: 'Cyborg' cockroaches breathe underwater with printed suit.

Nature·2026
Same journal

China boosts prestigious grants for young scientists - will it ease competition?

Nature·2026
Same journal

Incoming US science academy chief vows to 'double down' on research.

Nature·2026
Same journal

Author Correction: Synthesis of enantioenriched atropisomers by biocatalytic deracemization.

Nature·2026
Same journal

Electrodeposited self-assembled molecules for perovskite photovoltaics.

Nature·2026
Same journal

Neutrino's nursery found: the 'Shadow Blaster'.

Nature·2026
查看所有相关文章

科学领域:

  • 酵母遗传学 酵母遗传学
  • 进化生物学是进化的生物学.
  • 基因组学就是基因组学.

背景情况:

  • 萨卡罗米克斯'sensu stricto'酵母交配,但产生无菌的杂交.
  • 以前的研究发现染色体转位与这些酵母的物种化无关.
  • 基因组重组在生殖隔离中的作用仍然不清楚.

研究的目的:

  • 调查基因组对线性在Saccharomyces物种化中的作用.
  • 通过实验评估染色体转位对杂交活力和生育能力的影响.

主要方法:

  • 重构了Saccharomyces cerevisiae基因组,使其与Saccharomyces mikatae对齐.
  • 在工程S. cerevisiae和野生类型物种之间进行的交叉.
  • 分析了杂交子的生存能力和性.

主要成果:

  • 在S. cerevisiae x S. mikatae杂交物种中强加的基因组对线性产生了可行的但无体子.
  • 同样的结果在与自然对齐的物种Saccharomyces paradoxus交叉时也得到了观察.
  • 非对线交叉不产生可活的无细胞体子.

结论:

  • 基因组对线性影响Saccharomyces的杂交活力和 ploidy.
  • 染色体转位可能会导致生殖隔离障碍.
  • 这项研究表明,在S. cerevisiae中产生基因组冗余的机制.