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Updated: May 2, 2026

Spatio-Temporal Manipulation of Small GTPase Activity at Subcellular Level and on Timescale of Seconds in Living Cells
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Published on: March 9, 2012

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关于Ras.GTP对Ras特异性核酸交换因子SOS的反激活的结构证据

S Mariana Margarit1, Holger Sondermann, Brian E Hall

  • 1Department of Molecular Genetics and Microbiology, State University of New York at Stony Brook, Stony Brook, NY 11794, USA.

Cell
|March 12, 2003
PubMed
概括

增长因子受体通过七无之子 (SOS) 激活Ras. Ras.GTP结合一个独特的SOS位点,以全稳定活性位点,并为Ras调节创建一个积极的反循环.

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