Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Long-term Potentiation01:35

Long-term Potentiation

Long-term potentiation, or LTP, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTP is the process of synaptic strengthening that occurs over time between pre- and postsynaptic neuronal connections. The synaptic strengthening of LTP works in opposition to the synaptic weakening of long-term depression (LTD) and together are the main mechanisms that underlie learning and memory.
Role of Neurotransmitters in Memory01:23

Role of Neurotransmitters in Memory

Neurotransmitters are integral to the brain's communication system, enabling neurons to transmit signals across synapses. This chemical exchange underpins various cognitive functions, including memory processes. The role of neurotransmitters in memory is multifaceted, influencing the encoding, consolidation, and retrieval of memories through their action on different neural circuits.
 Glutamate and Synaptic Plasticity
Glutamate, the brain's main excitatory neurotransmitter, is critical for...

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Distinct roles of neuronal phenotypes during neurofeedback adaptation.

PloS one·2026
Same author

Value coding by primate amygdala neurons complies with the continuity axiom of economic choice theory.

Journal of neurophysiology·2026
Same author

Full dopamine coding of basic economic subjective value: Utility and weighted probability.

Cell reports·2026
Same author

Dopamine and serotonin neurotransmissions exert complementary control over primate approach and avoidance.

Translational psychiatry·2025
Same author

Learning reduces ingroup bias more with perceived losses than gains across cultures.

NPJ science of learning·2025
Same author

Improving numerical measures of human feelings: The case of pain.

Social science & medicine (1982)·2025

相关实验视频

Updated: Jul 13, 2026

A Fully Automated and Highly Versatile System for Testing Multi-cognitive Functions and Recording Neuronal Activities in Rodents
09:13

A Fully Automated and Highly Versatile System for Testing Multi-cognitive Functions and Recording Neuronal Activities in Rodents

Published on: May 3, 2012

多巴胺神经元对奖励概率和不确定性的离散编码.

Christopher D Fiorillo1, Philippe N Tobler, Wolfram Schultz

  • 1Institute of Physiology, University of Fribourg, CH-1700 Fribourg, Switzerland. cdf28@cam.ac.uk

Science (New York, N.Y.)
|March 22, 2003
PubMed
概括
此摘要是机器生成的。

多巴胺神经元信号奖励预测错误和一个新的不确定性相关的反应. 这种不确定性编码可能会影响基于注意力的学习和承担风险的行为.

更多相关视频

Closed-loop Neuro-robotic Experiments to Test Computational Properties of Neuronal Networks
11:18

Closed-loop Neuro-robotic Experiments to Test Computational Properties of Neuronal Networks

Published on: March 2, 2015

Decoding Natural Behavior from Neuroethological Embedding
08:00

Decoding Natural Behavior from Neuroethological Embedding

Published on: October 3, 2025

相关实验视频

Last Updated: Jul 13, 2026

A Fully Automated and Highly Versatile System for Testing Multi-cognitive Functions and Recording Neuronal Activities in Rodents
09:13

A Fully Automated and Highly Versatile System for Testing Multi-cognitive Functions and Recording Neuronal Activities in Rodents

Published on: May 3, 2012

Closed-loop Neuro-robotic Experiments to Test Computational Properties of Neuronal Networks
11:18

Closed-loop Neuro-robotic Experiments to Test Computational Properties of Neuronal Networks

Published on: March 2, 2015

Decoding Natural Behavior from Neuroethological Embedding
08:00

Decoding Natural Behavior from Neuroethological Embedding

Published on: October 3, 2025

科学领域:

  • 神经科学是一个神经科学.
  • 计算神经科学是一种神经科学.
  • 决策神经科学 决策神经科学

背景情况:

  • 不确定性对于信息处理和预测准确性至关重要.
  • 概率 (P) 决定了不确定性,在P=0.5达到峰值,并且随着P接近0或1而下降.

研究的目的:

  • 研究多巴胺神经元活动如何与奖励概率和不确定性有关.
  • 识别与决策不确定性相关的神经信号.

主要方法:

  • 利用不同的刺激来表示不同的奖励概率.
  • 记录了多巴胺神经元在响应刺激时的阶段激活.
  • 分析了整个奖励概率的全谱的神经活动.

主要成果:

  • 多巴胺神经元阶段激活与概率单调变化,与奖励预测错误编码一致.
  • 一个新的,以前没有观察到的神经反应逐渐增加了不确定性,直到奖励交付.
  • 发现这种新的反应与不确定性水平有所不同.

结论:

  • 多巴胺信号编码奖励预测错误和不确定性.
  • 新发现的不确定性编码反应表明多巴胺在基于注意力的学习中发挥了作用.
  • 多巴胺在处理不确定性的作用可能延伸到冒险行为.