室内冠状动脉血管预防室内射频损伤的形成:对线性废除的含义
1Virginia Commonwealth University's Medical College of Virginia, Richmond, USA.
Circulation
|April 1, 2003
概括
小血管中的血液流动可以防止外壁射频 (RF) 损伤的形成,并保持导电性. 这种血管效应可能会阻碍在临床环境中产生线性射频病变.
科学领域:
- 心血管研究研究心血管研究
- 电子生理学 电子生理学
- 医疗器械技术 医疗器械技术
背景情况:
- 射频 (RF) 病变附近的血液流动会导致对流冷却,减少病变大小.
- 射频病变中的血液流动对外壁病变形成的影响尚不清楚.
研究的目的:
- 为了研究通过小心内血管的血液流动是否可以防止外壁病变的形成.
- 评估血管输液对通过射频损伤传导的作用.
主要方法:
- 在子的右心室中创建了RF病变,跨越了透的动脉.
- 在不同温度 (60°C,80°C) 和 perfusion 速率 (0-12 mL/min) 的情况下造成了病变.
- 进行了组织学分析和导电测量.
主要成果:
- 即使是通过动脉的最小血流 (1毫升/分钟) 也可以防止跨壁病变的形成.
- 需要高的能量和温度来克服输液的保护作用.
- 保存的组织体积与 perfusion 速率,动脉直径和损伤温度相关.
- 导电通过血管 perfusion 存在的病变持续存在.
结论:
- 在小血管中的心脏内血流阻碍了跨壁射频损伤的产生.
- 血管 perfusion 保存了组织和导电,可能会使临床 RF 剥离复杂化.
- 这些发现突出了在实现线性射频损伤方面未被识别的障碍.
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