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Updated: May 6, 2026

Generation of a Humanized Mouse Liver Using Human Hepatic Stem Cells
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移植骨髓通过细胞融合再生肝脏

George Vassilopoulos1, Pei-Rong Wang, David W Russell

  • 1Division of Hematology, University of Washington, Seattle, Washington 98195, USA.

Nature
|April 1, 2003
PubMed
概括

细胞融合,而不是干细胞,解释了移植的骨髓细胞如何在铁血病模型中再生肝脏组织. 捐赠者和宿主细胞合并,形成具有改变基因表达的多倍体肝细胞.

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