PAC1酸酶是p53的转录标,用于信号亡和增长抑制

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Updated: Jun 22, 2026

Identification of Intracellular Signaling Events Induced in Viable Cells by Interaction with Neighboring Cells Undergoing Apoptotic Cell Death
09:18

Identification of Intracellular Signaling Events Induced in Viable Cells by Interaction with Neighboring Cells Undergoing Apoptotic Cell Death

Published on: December 27, 2016

Yuxin Yin1, Yu-Xin Liu, Yan J Jin

  • 1Department of Radiation Oncology, College of Physicians and Surgeons, Columbia University, 630 West 168th Street, New York, New York 10032, USA.

Nature
|April 4, 2003
PubMed
概括

在亡过程中,瘤抑制剂p53激活了酸酶PAC1 (双特异性酸酶2). PAC1对于p53介导的亡和瘤抑制至关重要,揭示了一种新的基因调节机制.

关键词:
非编程性的非编程性.

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