低碳水化合物饮食的有效性和安全性:系统审查
Dena M Bravata1, Lisa Sanders, Jane Huang
1Center for Primary Care and Outcomes Research, Stanford University School of Medicine, Stanford, Calif 94305-6019, USA. bravata@healthpolicy.stanford.edu
JAMA
|April 10, 2003
概括
与卡路里限制和饮食持续时间相比,低碳水化合物饮食对减肥没有明显的好处. 需要更多的研究来确定特定人群和持续时间的疗效和安全性.
科学领域:
- 营养科学 营养科学
- 饮食干预 饮食干预
- 代谢健康 代谢健康
背景情况:
- 低碳水化合物饮食很受欢迎,但缺乏关于有效性和安全性的强有力的证据.
- 在文献中没有明确的低碳水化合物饮食定义.
研究的目的:
- 评估低碳水化合物饮食对体重,血清脂质,葡萄糖,胰岛素和成人血压的影响.
- 综合现有关于低碳水化合物饮食干预措施结果的证据.
主要方法:
- 从1966年到2003年对英语语言研究进行系统的文献搜索.
- 包括与成人门诊患者进行低碳水化合物饮食 (≥4天,≥500千卡/日) 报告宏观营养素含量的研究.
- 从107篇文章中抽取数据,描述了94项饮食干预措施,涉及3268名参与者.
主要成果:
- 研究在设计,碳水化合物含量,热量摄入量和持续时间方面高度异质.
- 肥胖患者的体重减轻与饮食持续时间和减少卡路里摄入量相关,而不是碳水化合物限制.
- 低碳水化合物饮食对血清脂质,葡萄糖,胰岛素或血压没有显著的不良影响.
结论:
- 没有足够的证据来推或反对低碳水化合物饮食,特别是对于50岁以上的人,超过90天的饮食,或非常低碳水化合物摄入量 (≤20g/d).
- 在研究中观察到的减肥主要与减少热量摄入量和更长的饮食持续时间有关,而不是减少碳水化合物.
相关概念视频
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Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in the...
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in the...
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