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外囊综合体是胰岛素将Glut4向血膜所需的

Mayumi Inoue1, Louise Chang, Joseph Hwang

  • 1Life Sciences Institute, Departments of Internal Medicine and Physiology, University of Michigan Medical Center, Ann Arbor, Michigan 48109, USA.

Nature
|April 11, 2003
PubMed
概括

胰岛素信号激活了G蛋白TC10,它将外囊成分EXO70招募到血膜中. 这种相互作用对胰岛素刺激的葡萄糖吸收至关重要,因为它通过指导Glut4囊泡融合.

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