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LRP:血管壁完整性和对动脉样硬化的保护中的作用

Philippe Boucher1, Michael Gotthardt, Wei-Ping Li

  • 1Department of Molecular Genetics, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-9046, USA.

Science (New York, N.Y.)
|April 12, 2003
PubMed
概括

低密度脂蛋白受体相关蛋白 (LRP1) 通过调节PDGF受体 (PDGFR) 信号,防止血管光滑肌肉细胞迁移和动脉样硬化. 失活LRP1导致PDGFR过度表达,促进血管损伤和疾病.

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