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Updated: May 24, 2026

Promoter Capture Hi-C: High-resolution, Genome-wide Profiling of Promoter Interactions
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一种基因表达抑制剂,其向的是阿尔法螺旋介导的蛋白相互作用

Shinichi Asada1, Yongmun Choi, Motonari Uesugi

  • 1The Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas 77030, USA.

Journal of the American Chemical Society
|April 24, 2003
PubMed
概括

研究人员发现了adamanolol,一种新型有机分子,通过破坏蛋白质相互作用来抑制Her2瘤基因表达. 这种化合物选择性地杀死Her2阳性乳腺癌细胞,提供了一个新的治疗途径.

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