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Updated: Jun 19, 2026

Reconstitution Of β-catenin Degradation In Xenopus Egg Extract
09:41

Reconstitution Of β-catenin Degradation In Xenopus Egg Extract

Published on: June 18, 2014

奇比 (Chibby) 是Wnt/Wingless通路的一个核β-catenin相关的对手

Ken-Ichi Takemaru1, Shinji Yamaguchi, Young Sik Lee

  • 1Howard Hughes Medical Institute, Room K536C Health Sciences Building, Campus Box 357750, Department of Pharmacology, and Center for Developmental Biology, University of Washington School of Medicine, Seattle, Washington 98195, USA.

Nature
|April 25, 2003
PubMed
概括

一种新发现的蛋白质Chibby抑制了β-catenin活性,这是许多癌症的关键驱动因素. 这一发现为Wnt/Wingless途径和潜在的癌症疗法提供了新的见解.

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