控制福利导管的化和阻塞
D J Stickler1, G L Jones, A D Russell
1Cardiff School of Biosciences, Cardiff University, Cardiff CF10 3TL, Wales, UK. stickler@cardiff.ac.uk <stickler@cardiff.ac.uk>
Lancet (London, England)
|May 3, 2003
概括
用 triclosan 溶液膨胀尿道导管气球可以防止 Proteus mirabilis 生物膜的阻塞. 这种新的方法可以确保超过7天的免费排水,与标准的充满水的气球不同.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 生物医学工程 生物医学工程
- 传染性疾病 传染性疾病
背景情况:
- 尿管和阻塞是常见的并发症,通常是由Proteus mirabilis形成的晶体生物膜引起的.
- 这一问题显著影响了需要长期内置膀导管的患者,导致不适和潜在的健康风险.
研究的目的:
- 研究三桑注入的保留气球在预防Proteus mirabilis生物膜形成和导管阻塞方面的有效性.
- 在实验室模型中评估triclosan的潜力,作为防止导管化的预防措施.
主要方法:
- 使用实验室模型模拟了感染Proteus mirabilis的福利导管膀.
- 保持气球被充满了10g/L的三松溶液或无菌水.
- 随着时间的推移,监测了导管排水和生物膜的形成.
主要成果:
- 带有充满三素溶液的气球的导管至少7天自由排水.
- 特里克洛桑浸了导管材料,完全抑制了晶体生物膜的形成.
- 用水膨胀的导管在24小时内被生物膜阻塞.
结论:
- 用 triclosan 溶液膨胀 Foley 导管保留气球是一种有效的方法,可以防止 Proteus mirabilis 生物膜的和阻塞.
- 这一策略为管理与长期内置尿导管相关的频繁并发症提供了有希望的方法.
更多相关视频
相关概念视频
Feedback Inhibition
Biochemical reactions are occurring constantly in cells, converting starting substances to different products, usually with the help of enzymes that speed the reactions. Without enzymes, it would take far too long for most reactions to occur to be useful to the cell!
Allosteric Regulation
Allosteric regulation of enzymes occurs when the binding of an effector molecule to a site that is different from the active site causes a change in the enzymatic activity. This alternate site is called an allosteric site, and an enzyme can contain more than one of these sites. Allosteric regulation can either be positive or negative, resulting in an increase or decrease in enzyme activity. Most enzymes that display allosteric regulation are metabolic enzymes involved in the degradation or...
Allosteric Regulation
Allosteric regulation of enzymes occurs when the binding of an effector molecule to a site that is different from the active site causes a change in the enzymatic activity. This alternate site is called an allosteric site, and an enzyme can contain more than one of these sites. Allosteric regulation can either be positive or negative, resulting in an increase or decrease in enzyme activity. Most enzymes that display allosteric regulation are metabolic enzymes involved in the degradation or...
Load-frequency control
Load-frequency control (LFC) is vital for maintaining power system stability, ensuring that frequency and power flows remain within acceptable limits during load changes. Turbine-governor control eliminates rotor accelerations and decelerations following load changes. However, a steady-state frequency error persists when the change in the turbine-governor reference setting is zero. In an interconnected power system, each area agrees to export or import a scheduled amount of power through...
Drug Control Governance: Regulatory Bodies and Their Impact
Drug control governance involves the oversight and regulation of pharmaceuticals to ensure their safety and efficacy while preventing illegal drug use and trafficking. Regulatory bodies, including the US Food and Drug Administration (FDA) and the European Union's European Medicines Agency (EMA), play a central role in this process. These agencies evaluate the safety and efficacy of drugs before they can be marketed. They fund clinical trials and assess the benefits and risks associated with a...
Bioreactor Controls-I
Maintaining optimal conditions within fermenters is essential for maximizing microbial productivity and ensuring process efficiency. This lesson focuses on key parameters—temperature, foam, pH, carbon dioxide, oxygen, and pressure—and their precise measurement and control strategies in fermentation systems.Temperature ControlTemperature regulation is critical due to the exothermic nature of many fermentation processes. In small laboratory fermenters, temperature is commonly monitored using...


