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Updated: Aug 2, 2026

Visualization of Larval Segmental Nerves in 3rd Instar Drosophila Larval Preparations
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Published on: September 29, 2010

迪内因突变将运动神经元退化与逆行运输缺陷联系起来

Majid Hafezparast1, Rainer Klocke, Christiana Ruhrberg

  • 1Department of Neurodegenerative Disease, Institute of Neurology, National Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, UK.

Science (New York, N.Y.)
|May 6, 2003
PubMed
概括

细胞质二烯酸重链中的Missense突变会导致小鼠中运动神经元的渐进性退化. 这种病理类似于像ALS这样的人类神经退行性疾病,这表明这些疾病中的dynein功能障碍.

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Analyzing Mitochondrial Transport and Morphology in Human Induced Pluripotent Stem Cell-Derived Neurons in Hereditary Spastic Paraplegia

Published on: February 9, 2020

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