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Updated: May 5, 2026

Spatio-Temporal Manipulation of Small GTPase Activity at Subcellular Level and on Timescale of Seconds in Living Cells
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Published on: March 9, 2012

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动因动力学通过调节其协活性剂MAL来控制SRF活性

Francesc Miralles1, Guido Posern, Alexia-Ileana Zaromytidou

  • 1Transcription Laboratory, Room 401, Cancer Research UK London Research Institute, Lincolns Inn Fields Laboratories, 44 Lincoln's Inn Fields, London WC2A 3PX, UK.

Cell
|May 7, 2003
PubMed
概括

罗GTPases通过调节活性蛋白聚合来控制转录因子SRF. 这项研究揭示了Rho-actin信号引导SRF联合激活器MAL的核定位,这是SRF活动的关键机制.

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