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Updated: Jul 15, 2026

Functional Characterization of Na+/H+ Exchangers of Intracellular Compartments Using Proton-killing Selection to Express Them at the Plasma Membrane
07:38

Functional Characterization of Na+/H+ Exchangers of Intracellular Compartments Using Proton-killing Selection to Express Them at the Plasma Membrane

Published on: March 30, 2015

充电优化可以提高胆酸盐突变酶抑制剂的效力和选择性

Ajay Mandal1, Donald Hilvert

  • 1Laboratorium für Organische Chemie, Swiss Federal Institute of Technology, ETH Hönggerberg, CH-8093 Zürich, Switzerland.

Journal of the American Chemical Society
|May 8, 2003
PubMed
概括

计算电荷优化改进了可里斯马特突变酶抑制. 修改二碳酸盐抑制剂与基组增强强效和选择性对抗细菌细菌的 chorismate 突变酶 (BsCM).

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