Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Pinching-off of Coated Vesicles01:32

Pinching-off of Coated Vesicles

Vesicle budding is orchestrated by distinct cytosolic proteins such as adaptor proteins, coat proteins, and GTPases. To initiate vesicle budding, membrane-bending proteins containing crescent-shaped BAR domains bind to the lipid heads in the bilayer and distort the membrane to form a protein-coated vesicle bud. Adaptors proteins such as AP2 for clathrin-coated vesicles can nucleate on the deformed membrane. Finally, coat proteins such as clathrin or COPI and COPII assemble into a coat forming...
Cell Motility through Blebbing01:16

Cell Motility through Blebbing

Blebs are a type of membrane protrusion formed by the internal hydrostatic pressure of the cytoplasm. Blebs are observed in several cell types, including fibroblasts, immune cells, and single-celled organisms like the amoeba. The primary function of blebs is cell locomotion and apoptosis, but they are also found during necrosis and cell division. The life cycle of a bleb comprises an initiation phase followed by the expansion and retraction phases.
Blebbing Through the Matrix
In multicellular...

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Reversible bending of U-shaped plant petioles under dehydration.

Quantitative plant biology·2025
Same author

Bubble removal in microfluidic channels surrounded by gas-permeable media: experiments and a predictive model.

Lab on a chip·2025
Same author

In situ cavitation bubble manometry reveals a lack of light-activated guard cell turgor modulation in bryophytes.

Proceedings of the National Academy of Sciences of the United States of America·2025
Same author

Statistical Mechanics Approach to DNA-Driven Droplet Deformation and Adhesion.

Physical review letters·2025
Same author

Cell Deformation Signatures along the Apical-Basal Axis: A 3D Continuum Mechanics Shell Model.

ArXiv·2025
Same author

Near-field acoustic imaging with a caged bubble.

Nature communications·2024

相关实验视频

Updated: Jul 12, 2026

A Microfluidic System with Surface Patterning for Investigating Cavitation Bubble(s)–Cell Interaction and the Resultant Bioeffects at the Single-cell Level
11:14

A Microfluidic System with Surface Patterning for Investigating Cavitation Bubble(s)–Cell Interaction and the Resultant Bioeffects at the Single-cell Level

Published on: January 10, 2017

通过单个振荡泡进行控制的囊泡变形和溶解.

Philippe Marmottant1, Sascha Hilgenfeldt

  • 1Faculty of Applied Physics, University of Twente, PO Box 217, 7500AE Enschede, The Netherlands. p.marmottant@tn.utwente.nl

Nature
|May 9, 2003
PubMed
概括

温和的泡振荡,而不是暴力的崩,可以破裂细胞膜. 这一发现为控制的微声学在细胞操纵和治疗中开辟了新的途径.

科学领域:

  • 声学 声学 在声学方面
  • 生物物理学的生物物理.
  • 细胞生物学 细胞生物学

背景情况:

  • 崩的气泡集中能量,驱动诸如化损伤和声化学等现象.
  • 超声波触发的微气泡增强了医学成像,并显示了基于声波的治疗潜力.
  • 在声波穿孔中,泡诱导的膜破裂的确切机制尚不清楚.

研究的目的:

  • 为了研究泡诱导的脂质膜破裂的机制.
  • 为了证明温和的泡振荡可以实现膜破裂.
  • 探索受控微声学在细胞操纵方面的潜力.

主要方法:

  • 实验利用微气泡的受控,线性振荡.
  • 观察和分析气泡动力学和随后的脂质膜破裂.
  • 微气泡作为微米尺度上的声学聚焦剂的应用.

主要成果:

  • 轻微的线性泡振荡足以诱导脂质膜破裂.
  • 在这种温和的振荡模式下,可以精确控制气泡动力学和声波穿.
  • 微声学,利用微气泡,被证明是精确操纵的可行工具.

结论:

更多相关视频

Obtention of Giant Unilamellar Hybrid Vesicles by Electroformation and Measurement of their Mechanical Properties by Micropipette Aspiration
09:29

Obtention of Giant Unilamellar Hybrid Vesicles by Electroformation and Measurement of their Mechanical Properties by Micropipette Aspiration

Published on: January 19, 2020

Induction of Microstreaming by Nonspherical Bubble Oscillations in an Acoustic Levitation System
08:19

Induction of Microstreaming by Nonspherical Bubble Oscillations in an Acoustic Levitation System

Published on: May 9, 2021

相关实验视频

Last Updated: Jul 12, 2026

A Microfluidic System with Surface Patterning for Investigating Cavitation Bubble(s)–Cell Interaction and the Resultant Bioeffects at the Single-cell Level
11:14

A Microfluidic System with Surface Patterning for Investigating Cavitation Bubble(s)–Cell Interaction and the Resultant Bioeffects at the Single-cell Level

Published on: January 10, 2017

Obtention of Giant Unilamellar Hybrid Vesicles by Electroformation and Measurement of their Mechanical Properties by Micropipette Aspiration
09:29

Obtention of Giant Unilamellar Hybrid Vesicles by Electroformation and Measurement of their Mechanical Properties by Micropipette Aspiration

Published on: January 19, 2020

Induction of Microstreaming by Nonspherical Bubble Oscillations in an Acoustic Levitation System
08:19

Induction of Microstreaming by Nonspherical Bubble Oscillations in an Acoustic Levitation System

Published on: May 9, 2021

  • 声波可以通过受控,温和的泡振荡来实现,而不仅仅是暴力的崩.
  • 微声学提供了一种可控制的细胞膜透和操纵方法.
  • 这项研究为新的治疗和微流体应用铺平了道路.