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Updated: May 5, 2026

Invasion of Human Cells by a Bacterial Pathogen
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病原性细菌通过一个协同的β-zipper附着在人体纤维菌素上

Ulrich Schwarz-Linek1, Jörn M Werner, Andrew R Pickford

  • 1Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK.

Nature
|May 9, 2003
PubMed
概括

诸如金黄色葡萄球菌 (Staphylococcus aureus) 和白斑炎球菌 (Streptococcus pyogenes) 这样的细菌病原体使用纤维素结合蛋白 (FnBPs) 来侵入宿主细胞. 这项研究揭示了这些细菌FnBPs如何形成串联β-zippers来结合纤维素蛋白模块,解释了一个关键的入侵机制.

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